Clinical Trials

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Extended Antibiotic Use May Boost Risk of Colorectal Cancer Precursor

Long use of antibiotics is associated with higher risk of colorectal adenoma, according to an observational study in Gut. Adenomas are precursors for most colorectal cancers.

A multi-institutional team of...


Link between ALS, Schizophrenia May Spur New Paths of Research

Amyotrophic lateral sclerosis and schizophrenia share genetic origins, according to recent research published in Nature Communications. That finding has the potential to change how neurological and psychiatric diseases are studied and furthers hopes of curing both conditions.


Tobacco Cessation Eases Depression Symptoms in Smokers, Research Shows

Smokers living with depression who quit the habit by using certain smoking cessation services could gain significantly improved mental health, according to a recent study in Annals of Behavioral Medicine.


A Breath of Foul Air: Pollution and Pediatric Diabetes Risk

Research at the University of Southern California has uncovered a link between air pollution and elevated risk of Type 2 diabetes among overweight Latino children.


Empagliflozin: A Transformative Approach to Diabetes?

A major trial demonstrated the glucose-lowering drug empagliflozin reduces cardiovascular morbidity and mortality in individuals with Type 2 diabetes and existing cardiovascular disease. Clinicians and researchers discuss how it does so and who is most likely to benefit.


Beta-amyloid Research Ignites Treatment Hopes for Alzheimer’s Disease

Results of a phase 1b clinical trial published in Nature reveal scientists may be one step closer to finding a treatment that safely impedes the biological progression of Alzheimer’s disease.


Study Finds Survival Benefit for Lung Cancer Patients Whose Depression Improves

Improving symptoms of depression in lung cancer patients is associated with longer survival, according to a recent study. The findings highlight the need for oncology physicians to address mental health issues their patients may be facing, experts say.


Clarifying the Effect of Smoking on Male Fertility

Recent research demonstrates the chief mechanism by which smoking damages sperm.


Complicating Cognition: Common Prostate Cancer Treatment Associated with Higher Dementia Risk

Androgen deprivation therapy (ADT) is a staple of treatment for prostate cancer, but a recent study adds to a growing body of evidence that it places men at higher risk of cognitive decline.


Alzheimer’s, Antipsychotics and Pneumonia: A Balancing Act

Recent research finds that regardless of the drug selected, physicians should exercise caution when prescribing antipsychotics to Alzheimer’s patients.